Superficial siderosis of the CNS associated with multiple cerebral cavernous malformation

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Superficial siderosis of the CNS associated with multiple cavernous malformations.

Superficial siderosis of the CNS due to chronic, recurrent subarachnoid hemorrhage is an uncommon and potentially debilitating disorder. The classic clinical manifestation is progressive bilateral sensorineural hearing loss (SNHL), although ataxia and pyramidal signs also are observed frequently. Cavernous malformations rarely present with subarachnoid hemorrhage. We describe an unusual case of...

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Cerebral cavernous malformation with giant cysts is rare and literature descriptions of its clinical features are few. In this case study, the authors describe the clinical symptoms, radiological findings, and pathological diagnosis of cerebral cavernous malformations with giant cysts, reviewing the relevant literature to clearly differentiate this from other disease entities. The authors prese...

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Cerebral Cavernous Malformation Panel

Cerebral cavernous malformations (CCMs) are collections of small blood vessels (capillaries) in the brain that are enlarged and irregular in structure. These closely clustered irregular dilated capillaries have abnormally thin walls, and they lack other support tissues, such as elastic fibers, which normally make them stretchy. As a result, the blood vessels are prone to leakage, which can caus...

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Intradural extramedullary cavernous malformation with extensive superficial siderosis of the neuraxis: Case report and review of literature

BACKGROUND Spinal cavernous malformations usually affect the vertebral bodies and are seldom intradural. Here, we report a rare spinal intradural-extramedullary cavernous malformation associated with extensive superficial siderosis along the neuraxis in a patient with radicular complaints. CASE DESCRIPTION A 60-year-old male presented with subacute headaches, intermittent fever, and acute bac...

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Superficial siderosis of the CNS: MR diagnosis and clinical findings.

PURPOSE To report the clinical and neuroradiologic findings of superficial siderosis of the CNS, due to chronic subarachnoid bleeding of unknown origin. MATERIALS AND METHODS We observed seven cases. The main clinical manifestations were progressive deafness and ataxia. Four patients had had previous cranial or cervical trauma, with root avulsion in two, many years before onset of deafness an...

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ژورنال

عنوان ژورنال: Neurology

سال: 2009

ISSN: 0028-3878,1526-632X

DOI: 10.1212/01.wnl.0000345359.14275.f2